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Journal: Journal of Inflammation Research
Article Title: Early Immune-Inflammatory Profiling and Prognostic Biomarkers in Patients with Acute Diquat Poisoning: A Multicenter Study with Exploratory Bioinformatics Analysis
doi: 10.2147/JIR.S547369
Figure Lengend Snippet: Immune cell counts and inflammatory cytokines were compared between patients with acute DQ poisoning and healthy controls. ( A ) Changes in the number of WBC, neutrophils, lymphocytes, and monocytes in patients with acute DQ poisoning (n = 145) compared to healthy controls (n = 48). ( B ) Changes in CD3 + T cells, CD3 + CD4 + T cells, CD3 + CD8 + T cells, B cells, and NK cells in patients with acute DQ poisoning (n = 27) compared to healthy controls (n = 48). ( C ) Changes in the levels of IL-2, IL-6, IL-4, IL-10, TNF-ɑ, and IFN-γ in patients with acute DQ poisoning (n = 50) compared to healthy controls (n = 48). **** P < 0.0001.
Article Snippet: Fluorescence-labeled monoclonal antibodies were used for staining, including: cluster of differentiation (CD)3-fluorescein isothiocyanate (FITC), CD8-phycoerythrin (PE), CD45-peridinin chlorophyll protein (PerCP), CD4-allophycocyanin (APC)/CD3-FITC, CD16+CD56-PE, CD19-APC/CD3-FITC, CD127-PE,
Techniques:
Journal: Journal of Inflammation Research
Article Title: Early Immune-Inflammatory Profiling and Prognostic Biomarkers in Patients with Acute Diquat Poisoning: A Multicenter Study with Exploratory Bioinformatics Analysis
doi: 10.2147/JIR.S547369
Figure Lengend Snippet: Comparison of T cell activation between patients with acute DQ poisoning and healthy controls. ( A ) Changes in CD3 + HLA-DR + T cells, CD3 + CD38 + T cells, CD3 + CD28 + T cells, and CD3 + CD69 + T cells between patients with acute DQ poisoning (n = 22) and healthy controls (n = 20). ( B ) Changes in CD3 + CD8 + HLA-DR + T cells, CD3 + CD8 + CD38 + T cells, CD3 + CD8 + CD28 + T cells, and CD3 + CD48 + CD69 + T cells between patients with acute DQ poisoning (n = 22) and healthy controls (n = 20). ( C ) Changes in CD3 + CD4 + HLA-DR + T cells, CD3 + CD4 + CD38 + T cells, CD3 + CD4 + CD28 + T cells, CD3 + CD4 + CD69 + T cells, and CD3 + CD4 + Treg T cells between patients with acute DQ poisoning (n = 22) and healthy controls (n = 20). ** P < 0.01, *** P < 0.001, **** P < 0.0001.
Article Snippet: Fluorescence-labeled monoclonal antibodies were used for staining, including: cluster of differentiation (CD)3-fluorescein isothiocyanate (FITC), CD8-phycoerythrin (PE), CD45-peridinin chlorophyll protein (PerCP), CD4-allophycocyanin (APC)/CD3-FITC, CD16+CD56-PE, CD19-APC/CD3-FITC, CD127-PE,
Techniques: Comparison, Activation Assay
Journal: Journal of Inflammation Research
Article Title: Early Immune-Inflammatory Profiling and Prognostic Biomarkers in Patients with Acute Diquat Poisoning: A Multicenter Study with Exploratory Bioinformatics Analysis
doi: 10.2147/JIR.S547369
Figure Lengend Snippet: Immune cell counts and inflammatory cytokines were compared between the survival and death groups. ( A ) Changes in the number of WBC, neutrophils, lymphocytes, and monocytes in the death groups (n = 72) compared to the survival groups (n = 73). ( B ) Changes in CD3 + T cells, CD3 + CD4 + T cells, CD3 + CD8 + T cells, NK cells, and B cells in the death groups (n = 11) compared to the survival groups (n = 16). ( C ) Changes in levels of IL-2, IL-6, IL-4, IL-10, TNF-α, and IFN-γ in the death groups (n = 18) compared to the survival groups (n = 32). * P < 0.05, **** P < 0.0001.
Article Snippet: Fluorescence-labeled monoclonal antibodies were used for staining, including: cluster of differentiation (CD)3-fluorescein isothiocyanate (FITC), CD8-phycoerythrin (PE), CD45-peridinin chlorophyll protein (PerCP), CD4-allophycocyanin (APC)/CD3-FITC, CD16+CD56-PE, CD19-APC/CD3-FITC, CD127-PE,
Techniques: